Thanks @Craszar!
Have fun gaming!
Because the igo64.dll is a DLL that is part of the Origin overly, I also like you to test the costume launcher be devidedbyzero again.
It is now drag and drop, meaning all you have to do is to rename the "MassEffectLauncher.exe" under "<drive>:\Program Files (x86)\Origin Games\Mass Effect Legendary Edition\Game\Launcher" into "Old_MassEffectLauncher.exe".
Then you copy the costume launcher into "<drive>:\Program Files (x86)\Origin Games\Mass Effect Legendary Edition\Game\Launcher" and try to start the game from the new launcher.
At this point we are running out of options regarding a online troubleshot.
All I can suggest now is a Windows repair installation that would allow to keep al files and all programs, checking if all Hardware drivers on your system are up to date, checking if your BIOS is up to date.
A later Patch of the game might fix the incompatibility but because I don't know what the exact problem is, I can't promises that.
Please create a DxDiag in text file format and post it with your next reply. You can do that with the "Choose file" button at the bottom right corner of the reply window.
