Alternate leadership for specific squads

I tend to prefer Asajj lead, but that largely is because my NS are undergeared and undermodded. So having the tmr not be resisted is more useful. If I were serious about running NS though and had propper gear and mods, it may turn out that Talzin is overall better and the plague is better than the offense and tmr. But it probably still may depend on the enemy. There are definitely places where people get one-tracked into certain squad arrangements: Case in point, people so often default to Palp leads that they choice him for lead in a GC against Bastila lead, where most if not all of his lead is wasted as Bastila is a hard counter to Palp teams. Vader would've been a much better choice (not that it mattered as much in this particular example when you learned to stack the event ability with Vader).

Brood Alpha I would take the hardline is way better than Poggle though. It's not just extra health and protection, it's health steal and protection recovery. With the zeta, the extra damage on basics per buffed enemy can rival the offense from Poggle lead provided the enemy is still getting buffed.

Poggle lead would be useful with Droideka or something for a leftovers 3x3 team, and even that is generous. I can't say you should ever use Poggle lead except when you're forced to in that p1 TB mission, but then having it maxed is just a matter of pride for your own CM mission waves if your guild is 6-starring p1 anyway.