@mikrolactaki3 This thread isn't close to dead; I personally only start wishing someone would create a new one after about a year.
Anyway, options.ini doesn't store your graphics card info. It does record the driver version, but deleting it and letting the game create a new one has no effect on what card the game uses. Deleting it is a good idea though just to let the graphics settings return to defaults.
Mods are unaffected by deleting options.ini because their settings for a particular save are stored within the save files themselves. Saves could be affected if you load a current save with different options than you've been using, but that depends on the setting. To avoid that, just start a new save for testing, reset the options to what you want within that save, and if everything is fine, go back to your existing saves afterwards.
