@kimgetz Okay, try repairing the game in Origin if you haven't already. (Right-click on the Sims 4 icon in your game library and select Repair.) Then test.
If that doesn't help, again with a single save and nothing else in an otherwise clean folder, please try loading a different household and playing with them instead. One day should be more than long enough; you can fast forward if you want. Then save, quit, reload, and switch back to your original sims.
If that doesn't help either, let me know whether your computer runs Windows or macOS. This may be an issue of automatic cloud syncing (OneDrive or iCloud, respectively); you can test by disabling auto sync or turning off cloud storage entirely.
It is most definitely iCloud. It must be corrupting the file somehow. Thank you!
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