Issues w/ Gameplay

I don't know if I'll be able to state my issue clearly, but I'll try. I start up the game, hit resume game, and everything loads fine. However, once I start clicking around or try to go to a different sim, the game kind of freezes. The Sims still move; however, time has stopped. I cannot click on anything, save, or use the quit button. I have to manually shut it down using Task Manager. I've tried removing my custom content (no mods), removing old files and caches, but I have no idea what to do from this point. Any help would be appreciated. 

Thank you! :)