Origin - Home page, game library, my profile not loading

@NidhiBaliga  Program files can't be shifted manually from one drive to another; they have to be uninstalled and reinstalled.  For TS3, you'll need to clean the registry before reinstalling, either manually or with a tool like Piriform's CCleaner.

https://help.ea.com/en-us/help/the-sims/the-sims-3/manually-uninstalling-the-sims-3/

If your installation process is tied to Origin, it's probably better that you install directly through Origin, rather than from your discs.  Origin and disc installs are supposed to work together, but they don't always, especially if you later buy digital copies of packs.

You'll also need to redirect your Documents folder to E.  TS3 will look for its game folder in Documents no matter where you put the Electronic Arts folder; if the game doesn't find its folder, it will create a new one from scratch, so your saves and the rest of your content in your existing folder won't load the next time you launch the game.

For the Origin error, once you've uninstalled TS3, you can clear Origin's cache.  If that doesn't work, try uninstalling Origin itself ("the hard way").

https://help.ea.com/en-us/help/faq/clear-cache-to-fix-problems-with-your-games/

https://help.ea.com/en-us/help/origin/origin/manually-uninstalling-origin/