You didn't mention using the Ley Line Lot Trait on your lot. I am also doing the 100 Babies Challenge and I have had MANY twins. My first generations Matriarch had 22 babies in 13 pregnancies. Only 4 pregnancies were singles. I don't use any cheats or mods that would affect her having twins. Just the Lot Trait and the Fertile Reward Trait. I am barely into the 2nd Generation. She had 2 singles and then I realized that I had forgotten the Ley Line lot trait and changed it and her next pregnancy was twins. I have not had triplets in this Save, but in my Legacy Family, I have had two sets of triplets. In both cases, I had on the Ley Line Trait, the occult ley line trait (they are Spellcasters), then I use a Fertilty Massage, plus used a Fertility potion (from Herbalism). The other thing is-and I'm not sure if this works-is during the whole pregnancy I listen to Kids Radio. I read somewhere that that will encourage multiples. I have no idea if it's true. But overall, it is rare for me to have a single birth and it is usually when I am at 7 in the household and there just isn't room for anymore than a single.