In my rotational save, Darling Welsh is trans and living his best life in an apartment in San Myshuno. I wanna eventually set him up with Morgan Fyres, but that's going to take a couple of rotations to get there with them. Not to mention he's currently engaged to J Huntington III, but with J's reputation, that's not going to last long. Ah well. There's a prettier red-headed fish in the sea waiting for him once that relationship ends.
The blue generation spare in my Not So Berry save is trans as well. The game gave me the idea when it crashed shortly after my sim gave birth and I had to replay to that point. I was expecting the baby to have the same gender as last time, but that wasn't the case. Since Darling is the only other trans sim I have, I thought having another trans guy would be nice. I'd like to have some trans female sims one day as well.