Can you buy Vampires w/o having to deal with the Vampires?

If you're willing to use mods, I believe MCCC has "humanize all vampires" (and other occults) in the options.  Twisted Mexi also has a "no vampires" mod.

I don't think there's a way to do it without mods.

@EmMac1066 Hi!  I just wanted to add a couple things to @PoptartJuniper 's and @xochiquetzl_xkvn 's suggestions.  Vampires can be eliminated manually through Manage Worlds / Manage Households.  The Vampire pack adds the Forgotten Hollow world, which is inhabited by the premade vampires; Count Vladislaus Straud IV and the siblings Lillith and Caleb Vatore.  You have the option to eliminate these right away, if you wish.  Also, in my experience, the only one that will attempt to bite your played sims is Vladislaus.  As Poptart mentioned, you can lock your door to trespassers to prevent other vampires from intruding.  As for other game-generated vampires, you will only notice them if they fly as a bat (some can run really fast but I haven't noticed it for NPC sims other than Caleb and Lillith) or make their hissing noises.  If you do notice them, just make a note of their name, look for them in Manage Househoulds, and delete them. Without a mod, as xochiquetzl mentioned, there's no way to prevent them from appearing in the game.  However, after deleting Vladislaus, Lillith and Caleb, the chances of seeing others is limited I think.  

As for the Realm of Magic pack, if you never take your sims to the Magic Realm or have them become spellcasters, you'll never even notice the spellcaster sims.  Those NPCs do not do magic outside the Magic Realm, which is a semi-secret area that you can only travel to through a somewhat hidden portal or as a spellcaster.  Hope this helps!

Edit: BTW I love the clothing and build items too! :-)

What @JonaO703 said.  Caleb and Lilith come knock on your door, but if you let them in they'll chat with you and then use your computer or watch your television, lol.  :D  They don't sneak into your house or try to bite your Sims;  Caleb has the "Good Vampire" aspiration that's all about not biting people. (Er.  He's one of my favorite Sims, TBH, so you could cure him or use one of the mods I mentioned to turn him into a human if you didn't want to delete him, although it's your game and that's absolutely an option.)

Vladislaus will try to bite your Sims, but he hates witnesses.  He'll leave if anyone is awake and in the area.  When the pack was first released he would break into your house, then he stopped for the longest time, and now he's started again.  It's honestly more of a nuisance, though; he doesn't kill anyone.  He drinks blood, leaves the victim passed out on the floor, and leaves, and the victim wakes up tired and with a sore neck. My tent-dwelling Sim had no door to lock, so i had her just be nice to him and he left her alone and even called her and invited her over to offer to turn her into a vampire (she declined; she's all about that outdoorsy life). So even Vlad isn't that scary. 

I digress, though.  You don't want vampires in your game.  I've had random vampires spawn, so I would probably use a mod to be sure. 

@EmMac1066In my experience, Vlad was the 1st one to bite my sims and some random vamps were sneaking into my lot when the vampire pack was released, but now.. even I haven’t seen Vlad was sneaking in. I haven’t seen any random vampires around town. If you maybe get this situation, then type ‘testingcheats on’ on cheat console, then click Vlad with shift key, then, reset object. Vlad will be reset, and he will go back to his mansion. :D

I had Vampires and RoM for ages before I ever really did anything with them and Vlad has never attacked any of my sims - and I have actually started trying to get him to do it with no luck. lol

Usually when a sim first moves in somewhere, they will get a text message sometime after 10pm from Vlad acting like a creeper and telling him they have a nice neck and then...nothing.  If he does show up, he usually just wants to sit and watch TV. 

I do see Lilith and Caleb around more often, but if you didn't know they were vampires, you couldn't tell from their interactions - especially Caleb. As @xochiquetzl_xkvn already mentioned, he's just a sweetheart who wants to hangout and play computer games.

I consider them both to be fairly innocuous background packs. 

@Slytherclaw72 Hi!  You make some excellent points.  I realize what I'm about to share is straying a bit from the original question and I apologize for that.  If you actually want Vlad to break in and attack your sims, try sending him home when he knocks on the door and then have all your sims go to bed.  It doesn't happen every time but I think the game establishes a "bed time" around then and will have Vlad come back at some point.  He will not attempt a break-in if any sims are awake, which @xochiquetzl_xkvn also mentioned.  I've actually seen him come back and leave right away without knocking.  Basically, sending your sims to bed shortly after his initial visit will send a message, so to speak, that Vlad has a window of opportunity.  

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@JonaO703 Thank you for the tip. I usually send them to bed between 10 and dawn when I’m trying to get him to show up, but I’ve never sent him home after he knocks, I usually just wait for him to leave if the sim doesn’t happen to wake up. I’ll have to dust off my vampires save and give that a try. 😄

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@Slytherclaw72 Yes, so the better option would be to note what time Vlad comes knocking and send your sims to bed before the time he normally comes.  As long as all sims are sleeping when he comes, he will likely break in and feed. Again, straying from the original question, sorry.

Thank you, all for helping me. Upon playing the game, I found some useful information that might be the solution to my own issue. I realize some of these were suggested to me above. But I had no idea what they meant. :facepalm: LOL. I thought you could only evict people from the households, not actually delete ones, not in the world. 

So here are the answers for newbie Sim players  

1. How you can cure vampirism. 

You can research vampires and buy books about them. On the highest level, you will unlock the ability to make a cocktail that will turn a vampire back into a human. You will need to harvest plants to make this cocktail. I had my main Sim had learn this skill, and she gave it to the Vampire Sim. You cannot make a vampire drink the cocktail.  So I then switched to play that Vampire Sim, and he drank the cocktail to become human. They married b/c Caleb is just too darn cute. 

2. You can delete vampires in OTHER HOUSEHOLDS, even ones currently not in the world. Just go to Manage Households, note their names, select the other tab, "Other Households," and delete the vampires.