sproutedpup Clean-uninstalling the graphics driver would have wiped your previous settings, so it's not a surprise that this particular setting would have reverted.
Do you have access to another graphics card you could test with? I'm not saying that your current GPU is definitely faulty, only that it's enough of a possibility at this point to justify the work to swap out the card. If you can borrow one from a friend or family member, please do so and see how the game runs.
For an Nvidia GPU (or an Intel one if you know anyone that has one), you'd need to DDU the AMD driver before removing the card, remove it and install the new one, and then install the proper driver yourself, all with your computer offline. So download the correct driver first so that you don't have to go back online.