I can't play. Pls help me :(

Ama_LP​  The error code 22 is, these days at least, almost always antivirus-related.  So is in-game settings not saving, and often so is the inability to start a new game.  Do you have Controlled Folder Access running, and if so, does it help to disable it?  You may need to repair Sims 4 (again) afterwards.

If that doesn't help, please create a new admin Windows account and try playing there.  Make it local, as in, don't link it to your Microsoft account or any email address.  (You can skip that step and will be asked to answer some security questions instead.)  Make sure Controlled Folder Access is disabled while you're in this account before you try to play Sims 4.  You won't have to reinstall it, but your saves and other user data won't be available.