So many issues - Menu, locking up, what's up?

Hey all - 

Since the last download/update, my menu buttons are all jacked up. There are no icons / no normal drop downs. I've reinstalled but nothing is helping. If I go into build mode, once I'm out of build mode - I have to restart because all menu buttons vanish and the game just stalls. If I try to interact with an item, craft an item, etc. the game stalls and I have to restart. I've disabled mods / deleted mods, tried straight vanilla.

The game is not playable at this point.

Suggestions?